Eluciation of Organometallic Reaction Mechanisms by in-situ Mass Spectrometry

Scheme 4. Redox gold catalysis without using an external oxidant

Due to the direct sampling capability, we have applied liquid sample DESI-MS to detect Pd(0) species from Buchwald C-N coupling reaction.¹⁶

Furthermore, in collaboration with organic chemists, we have carried out an extensive study for elucidating reaction mechanisms^17-23, in particular, gold-mediated coupling reactions (Scheme 4), in which gold(III) complex was identified.

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