Biophotonics and Bioimaging Laboratory

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Publications

2016

  • Sui, B.; Bondar, M. V.; Anderson, D.; Rivera-Jacquez, H. J.; Masunov, A. E.; *Belfield, K. D. “New Two-Photon Absorbing BODIPY-Based Fluorescent Probe: Linear Photophysics, Stimulated Emission and Ultrafast Spectroscopy” Journal of Physical Chemistry C 2016, 120, in press.

  • Sui, B.; Liu, X.; Wang, M.; *Belfield, K. D. “Highly Selective Fluorescence Turn-on Sensor for Extracellular Ca2+ Detection” Chemistry A European Journal 2016, 22, in press.

  • Wang, M.; Zhang, Y.; Yue, X.; Yao, S.; Bondar, M. V.; *Belfield, K. D. “A Deoxyuridine-Based Far-Red Emitting Viscosity Sensor” Molecules 2016, 21(6), 709 pp. 1-12; doi:10.3390/molecules21060709

  • Liu, T.; *Bondar, M. V.; *Belfield, K. D.; Anderson, D.; Masunov, A. E.; Hagan, D. J.; *Van Stryland, E. W. “Linear Photophysics and Femtosecond Nonlinear Spectroscopy of a Star-shaped Squaraine Derivative with Efficient Two-photon Absorption” Journal of Physical Chemistry C 2016, 120, 11099-11110.

  • Qiu, Y.; Wang, Y.; Belfield, K. D.; *Liu, X. “Ultrathin Lensed Fiber-optic Probe for Optical Coherence Tomography” Biomedical Optics Express 2016, 7, 2154-2162.

  • Sui, B.; Tang, S.; Woodward, A. W.; Kim, B.; *Belfield, K. D. “A New BODIPY-based Water-soluble Fluorescent Probe for Mitochondria Targeting” European Journal of Organic Chemistry 2016, 2851-2857.

  • Ballestas-Barrrientos, A. R.; Woodward, A. W.; Moreshead, W. V.; Bondar, M. V.; *Belfield, K. D. “Synthesis and Linear and Nonlinear Photophysical Characterization of Two Symmetrical Pyrene-terminated Squaraine Derivatives” Journal of Physical Chemistry C 2016, 120, 7829-7838.

  • Kurhuzenkau, S. A.; Woodward, A. W.; Yao, S.; Belfield, K. D.; Shaydyuk, Y. O.; Sissa, C.; *Bondar, M. V.; *Painelli, A. “Ultrafast Spectroscopy, Superluminescence and Theoretical Modeling of a Two-photon Absorbing Fluorene Derivative” Physical Chemistry Chemical Physics 2016, 18, 12839-12846.

  • Ali, M.; Kim, B.; Belfield, K. D.; Norman, D.; Brennan, M.; *Ali, G. S. “Green Synthesis and Characterization of Silver Nanoparticles using Artemisia Absinthium Aqueous Extract — A Comprehensive Study” Materials Science and Engineering C 2016, 58, 359-365.

2015

  • Sui, B.; Yue, X.; Kim, B.; *Belfield, K.D. “Near-IR Two-Photon Fluorescent Sensor for K+ Imaging in Live Cells” ACS Applied Materials and Interfaces 2015, 7, 17565-17568.

  • Yue, X.; Morales, A. M.; Githaiga, G. W.; Woodward, A. W.; Tang, S.; Sawada, J.; Komatsu, M.; Liu, X.; *Belfield, K. D. “RGD-conjugated Two-photon Absorbing Near-IR Emitting Fluorescent Probes for Tumor Vasculature Imaging” Organic and Biomolecular Chemistry 2015, 13, 10716-10725.

  • Ghazvini Zadeh, E. H.; Tang, S.; Woodward, A. W.; Liu, T.; Bondar, M. V.; Belfield, K. D. “Chromophoric Materials Derived From a Natural Azulene: Syntheses, Halochromism and One-photon and Two-photon Microlithography” Journal of Materials Chemistry C 2015, 3, 8495-8503.

  • Kim, B.; Yue, X.; Sui. B.; Zhang, X.; *Xiao, Y.; Bondar, M. V.; Sawada, J.; Komatsu, M.; *Belfield, K. D. “Near-infrared Fluorescent 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene Probes for One- and Two-photon Fluorescence Bioimaging” European Journal of Organic Chemistry 2015, 5563-5571.

  • Ghazvini Zadeh, E. H.; Bondar, M. V.; Mikhailov, I. A.; *Belfield, K. D. “Linear Photophysics, Stimulated Emission and Ultrafast Spectroscopy of New Two-Photon Absorbing Diketopyrrolopyrrole Derivatives” Journal of Physical Chemistry C 2015, 119, 8864-8875.

  • Irfan, M.; Belfield, K. D.; *Saeed, A. “Carbazole/Fluorene Based Conjugated Small Molecules: Synthesis and Comparative Studies on the Optical, Thermal and Electrochemical Properties” RSC Advances 2015, 5, 48760-48768.

  • *Ali, M.; Kim, B; Belfield, K. D.; Norman, D.; Brennan, M.; Ali, G. S. “Inhibition of Phytophthora parasitica and P. capsici by Silver Nanoparticles Synthesized using Aqueous Extract of Artemisia absinthium” Phytopathology 2015, 105, 1183-1190.

  • Ghazvini Zadeh, E. H.; Woodward, A. W.; Richardson, D.; Bondar, M. V.; *Belfield, K. D. “Stimuli-Responsive Cyclopenta[ef]heptalenes: Synthesis and Optical Properties” European Journal of Organic Chemistry 2015, 2271-2276.

  • Yue, X.; Armijo, Z.; King, K.; Bondar, M. V.; Morales, A. R.; Frazer, A.; Mikhailov, I. A.; Przhonska, O. V.; *Belfield, K. D. “Steady-state and femtosecond transient absorption spectroscopy of new two-photon absorbing fluorene-containing quinolizinium cation membrane probes” ACS Applied Materials and Interfaces 2015, 7, 2833-2846.

  • Sui, B.; Yue, X.; Tichy, M. G.; Liu, T.; *Belfield, K. D. “Improved Synthesis of the Triazacryptand (TAC) and its Application in the Construction of a Fluorescent TAC-BODIPY Conjugate for K+ Sensing in Live Cells” European Journal of Organic Chemistry 2015, 1189-1192.

2014

  • Sui, B.; Tang, S.; Liu, T.; Kim, B.; *Belfield, K. D. “Novel BODIPY-based Fluorescence Turn-on Sensor for Fe3+ and its Bioimaging Application in Living Cells” ACS Applied Materials and Interfaces 2014, 6, 18408-18412.

  • Woodward, A. W.; Frazer, A.; Morales, A. M.; Yu, J.; Moore, A. F.; Campiglia, A. D.; Jucov, E. V.; Timofeeva, T. V.; *Belfield, K. D. “Two-photon sensitized visible and near-IR luminescence of lanthanide complexes using a fluorene-based donor-π-acceptor diketonate” Dalton Transactions 2014, 43, 16626-16639.

  • *Belfield. K. D.; Bondar, M. V.; Yao, S.; Mikhailov, I. A.; Polikanov, V. S.; Przhonska, O. V. “Femtosecond Spectroscopy of Superfluorescent Fluorenyl Benzothiadiazoles with Large Two-Photon and Excited State Absorption” Journal of Physical Chemistry C 2014, 118, 13790-13800. DOI: 10.1021/jp503106k

  • Bashmakova, N.V.; Shaydyuk, Y.O.; Levchenko, S.M.; Masunov, A.E.; Przhonska, O.V.; Bricks, J.L.; Kachkovsky, O.D.; Slominsky, Y.L.; Piryatinski, Y.P.; Belfield, K.D.; *Bondar, M.V. “Design and Electronic Structure of New Styryl Dye Bases: Steady-State and Time-Resolved Spectroscopic Studies.” Journal of Physical Chemistry A 2014, 118, 4502-4509.

  • Zhang, Y.; Yue, X.; Kim, B.; Yao, S.; *Belfield, K. D. “Deoxyribonucleoside Modified Squaraines as Near-IR Viscosity Sensors” Chemistry – A European Journal 2014, 20, 7249-7253

  • Frazer, A.; Morales, A. R.; Woodward, A. W.; Tongwa, P.; Timofeeva, T.; *Belfield, K. D. “Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection” Journal of Fluorescence 2014, 24, 239-250.

2013

  • Moreshead, W. V.; Przhonska, O. V.; Bondar, M. V.; Kachkovski, A. D.; Nayyar, I. H.; Masunov, A. E.; Woodward, A. W.; Belfield, K. D. “Design of a New Optical Material with Broad Spectrum Linear and Two-Photon Absorption and Solvatochromism” The Journal of Physical Chemistry C 2013 117 (44), 23133-23147

  • Belfield, K. D., Bondar, M. V., Haniff, H. S., Mikhailov, I. A., Luchita, G. and Przhonska, O. V., “Superfluorescent Squaraine with Efficient Two-Photon Absorption and High Photostability.” ChemPhysChem 2013, 14: 3532–3542. doi: 10.1002/cphc.201300447

  • Zhang, Y.; Kim, B.; Yao, S.; Bondar, M. V.; Belfield, K.D. “Controlled Aggregation and Enhanced Two-Photon Absorption of a Water-Soluble Squaraine Dye with a Poly(acrylic acid) Template” Langmuir 2013 29 (35), 11005-11012

  • Zhang, Y.; Yue, X.; Kim, B.; Yao, S.; Bondar, M. V.; Belfield, K.D. “Bovine Serum Albumin Nanoparticles with Fluorogenic Near-IR-Emitting Squaraine Dyes”ACS Applied Materials & Interfaces 2013 5 (17), 8710-8717

  • Belfield, K. D.; Bondar, M. V.; Morales, A. R.; Frazer, F.; Mikhailov, I. A.; Przhonska, O. V. “Photophysical Properties and Ultrafast Excited-State Dynamics of a New Two-Photon Absorbing Thiopyranyl Probe” The Journal of Physical Chemistry C 2013 117 (23), 11941-11952

  • Zhao, K.; Liu, T.; Wang, G.; Chang, X.; Xue, D.; Belfield, K. D.; Fang, Y. “A Butterfly-Shaped Pyrene Derivative of Cholesterol and Its Uses as a Fluorescent Probe” The Journal of Physical Chemistry B 2013 117 (18), 5659-5667

  • Yanez, C.O.; Morales, A. R.; Yue, X.; Urakami, T.; Komatsu, M.; Jarvinen, T.A.H.; *Belfield, K. D. “Deep Vascular Imaging in Wounds by Two-Photon Fluorescence Microscopy” PLoS ONE 2013, 8(7), e67559. doi:10.1371/journal.pone.0067559

  • *Belfield, K. D.; Bondar, M. V.; Morales, A. R.; Frazer, A. F.; Mikhailov, I.; Przhonska, O. V. “Photophysical Properties and Ultrafast Excited State Dynamics of a New Two-Photon Absorbing Thiopyranyl Probe” Journal of Physical Chemistry C 2013, 117,11941-11952.

  • Sui, B.; Kim, B.; Zhang, Y.; Frazer, A.; *Belfield, K. D. “Highly Selective Fluorescence Turn-On Sensor for Fluoride Detection” ACS Applied Materials and Interfaces 2013, 5, 2290-2293.

  • Yue, X.; Yanez, C. O.; Yao, S.; *Belfield, K. D. “Selective Cell Death by Photochemically Induced pH Imbalance in Cancer Cells” Journal of the American Chemical Society 2013, 135, 2112-2115.

  • Morales, A. R.; Frazer, A.; Woodward, A. W.; Ahn-White, H.-Y.; Fonari, A.; Tongwa, P.; Timofeeva, T. V.; *Belfield, K. D. “Design, Synthesis, Structural and Spectroscopic Studies of Push-Pull Two-Photon Absorbing Chromophores with Acceptor Groups of Varying Strength” Journal of Organic Chemistry 2013, 78, 1014-1025.

  • Zhao, K.; Liu, T.; Wang, G.; Chang, X.; Xue, D.; Belfield, K. D.; *Fang, Y. “A Butterfly-Shaped Pyrene Derivative of Cholesterol and its uses as a Fluorescent Probe” Journal of Physical Chemistry B, 2013, 117, 5659-5667.

2012

  • Morales, A. R.; Yanez, C. O.; Zhang, Y.; Wang, X.; Biswas, T.; Komatsu, M.; *Belfield, K. D. “Small Molecule Fluorophore and Copolymer RGD Peptide Conjugates for Ex Vivo Two-Photon Fluorescence Tumor Vasculature Imaging” Biomaterials 2012, 33, 8477-8485.

  • *Belfield, K. D.; Bondar, M. V.; Morales, A. R.; Yue, X.; Luchita, G.; Przhonska, O. V.; Kachkovsky, O. D. “Two-Photon Absorption and Time-Resolved Stimulated Emission Depletion Spectroscopy of a New Fluorenyl Derivative” ChemPhysChem 2012, 13, 3481-3491.

  • Ahn, H.Y.; Yao, S.; Wang. X.; *Belfield, K. D. “Near-Infrared Emitting Squaraine Dyes with High 2PA Cross Sections for Multiphoton Fluorescence Imaging” ACS Applied Materials and Interfaces 2012, 4, 2847-2854.

  • *Belfield, K. D.; Bondar, M. V.; Morales, A. R.; Yue, X.; Luchita, G.; Przhonska, O. V. “Transient Excited-state Absorption and Gain Spectroscopy of a Two-Photon Absorbing Probe with Efficient Superfluorescent Properties” Journal of Physical Chemistry C 2012, 116, 11261-11271.

  • Yao, S.; *Belfield, K. D. “Two-photon Fluorescent Probes for Bioimaging” European Journal of Organic Chemistry 2012, 3199-3217.

  • Biswas, S.; *Belfield, K. D.; Das, R.; Ghosh, S.; Hebard, A. “Superparamagnetic Nanocomposites Templated with Pyrazole-containing Diblock Copolymers” Polymers 2012, 4, 1211-1225. DOI:10.3390/polym4021211

  • Ahn, H.-Y.; Fairfull-Smith, K. E.; Morrow, B. J.; Lussini, V.; Kim, B.; Bondar, M. V.; Bottle, S. E.; *Belfield, K. D. “Two-photon Fluorescence Microscopy Imaging of Cellular Oxidative Stress using Profluorescent Nitroxides” Journal of the American Chemical Society 2012, 134, 4721-4730.

  • Biswas, S.; Ahn, H-Y.; Bondar, M. V.; *Belfield, K. D. “Two-photon Absorption Enhancement of Polymer-templated J-aggregates” Langmuir 2012, 28, 1515-1522.

  • Qaddoura, M. A.; *Belfield, K. D.; Heiney, P. A. “Liquid Crystal-directed Assembly and Phase Morphology of a Squaraine Dye” Supramolecular Chemistry 2012, 24, 299-311. DOI:10.1080/10610278.2012.658391

  • *Spencer, S.; Hu, H.; Li, Q.; Ahn, H.-Y.; Qaddoura, M.; Yao, S.; Ioannidis, A.; Belfield, K.; Collison, C. J. “Controlling J-aggregate Formation for Increased Short-circuit Current and Power Conversion Efficiency with a Squaraine Donor” Progress in Photovoltaics: Research and Applications 2012, doi: 10.1002/pip.2289.

  • Diaz, C.; Frazer, A.; Morales, A.; Belfield, K. D.; Ray, S.; *Hernandez, F. E. “Structural Identification of a Novel Axially Chiral Binaphthyl Fluorene Based Salen Ligand in Solution Using Electronic Circular Dichroism: A Theoretical Experimental Analysis” Journal of Physical Chemistry A 2012, 116, 2453-2465.

2011

  • Luchita, G.; Bondar. M. V.; Yao, S.; Mikhaylov, I. A.; Yanez, C. O.; Przhonska, O. V.; Masunov, A. E.; Belfield, K. D. “Efficient Photochromic Transformation of a New Fluorenyl Diarylethene: One- and Two-photon Absorption Spectroscopy” ACS Applied Materials and Interfaces 2011, 3, 3559-3567.

  • Andrade, C. D.; Yanez, C. O.; Ahn, H.-Y.; Urakami, T.; Bondar, M. V.; Komatsu, M.; Belfield, K. D. “Two-photon Fluorescence Vascular Bioimaging with New Bioconjugate Probes Selective Towards the Vascular Endothelial Growth Factor Receptor 2” Bioconjugate Chemistry 2011, 22, 2060-2071.

  • Qaddoura, M. A.; Belfield, K. D.; Tongwa, P.; DeSanto, J. E.; Timofeeva, T. V.; Heiney, P. A. “Thermotropic Behavior, Self-Assembly and Photophysical Properties of a Series of Squaraines” Supramolecular Chemistry 2011, 23, 731-742. DOI: 10.1080/10610278.2011.622391

  • Wang, X.; Morales, A. R.; Urakami, T.; Zhang, L.; Bondar, M. V.; Komatsu, M.; Belfield, K. D. “Folate Receptor-targeted Aggregation-enhanced Near-IR Emitting Silica Nanoprobe for One-photon in vivo and Two-photon ex vivo Fluorescence Bioimaging” Bioconjugate Chemistry 2011, 22, 1438-1450.

  • Biswas, S.; Wang, X.; Morales, A. R.; Ahn, H.-Y.; Belfield, K. D. “Integrin-targeting Block Copolymer Probes for Two-photon Fluorescence Bioimaging” Biomacromolecules 2011, 12, 441-449.

  • Belfield, K. D.; Bondar, M. V.; Hernandez, F. E.; Przhonska, O. V.; Wang, X.; Yao, S. “Superfluorescent Fluorenyl Probe with Efficient Two-photon Absorption” Physical Chemistry Chemical Physics 2011, 13, 4303-4310.

  • Andrade, C. D.; Yanez, C. O.; Qaddoura, M. A.; Wang, X.; Arnett, C. L.; Coombs, S. A.; Yu, J.; Bassiouni, R.; Bondar, M. V.; Belfield, K. D. “Two-Photon Fluorescence Lysosomal Bioimaging with a Micelle-Encapsulated Fluorescent Probe” Journal of Fluorescence 2011, 21, 1223-1230. DOI: 10.1007/s10895-010-0801-3

  • Tsuchikawa, R.; Ahn, H.-Y.; Yao, S.; Belfield, K. D.; Ishigami, M. “Photosensitization of carbon nanotubes using dye aggregates” Journal of Physics: Condensed Matter 2011, 23, 202204. doi:10.1088/0953-8984/23/20/202204

  • Belfield, K. D.; Bondar, M. V.; Morales, A. R.; Padhila, L. A.; Przhonska, O. V.; Wang, X. "Two-photon STED Spectral Determination for a New V-shaped Organic Fluorescent Probe with Efficient Two-photon Absorption" Chem. Phys. Chem. 2011, 12, 2755-276

2010

  • Nguyen, D. M.; Wang, X.; Ahn, H.-Y.; Rodriguez, L.; Bondar, M. V.; *Belfield, K. D. “Novel Hydrophilic Bis(1,2,3-triazolyl)fluorenyl Probe for in vitro Zinc Ion Sensing” ACS Applied Materials and Interfaces 2010, 2, 2978-2981. DOI: 10.1021/am100719v

  • Parthasarathy, A.; Ahn, H.-Y.; Belfield, K. D.; *Schanze, K. S. “Two-photon Excited Florescence of a Conjugated Polyelectrolyte and its Application in Cell Imaging” ACS Applied Materials and Interfaces 2010, 2, 2744-2748. DOI: 10.1021/am100784m

  • *Belfield, K. D.; Andrade, C. D.; Yanez, C. O.; Bondar, M. V.; Hernandez, F. E.; Przhonska, O. V. “New Two-Photon Absorbing Probe with Efficient Superfluorescent Properties” Journal of Physical Chemistry B 2010, 114, 14087-14095. DOI: 10.1021/jp107343k

  • Wang, X.; Nguyen, D. M.; Yanez, C. O.; Rodriguez, L.; Ahn, H.-Y.; Bondar, M. V.; *Belfield, K. D. “High Fidelity Hydrophilic Probe for Two-photon Fluorescence Lysosomal Imaging” Journal of the American Chemical Society 2010, 132, 12237-12239. DOI: 10.1021/ja1057423

  • Wang, X.; Yao, S.; Ahn, H.-Y.; Zhang, Y.; Bondar, M. V.; Torres, J. A.; *Belfield, K. D. “Folate Receptor Targeting Silica Nanoparticle Probe for Two-photon Fluorescence Bioimaging” Biomedical Optics Express 2010, 1, 453-462 (feature article).

  • *Belfield, K. D.; Bondar, M. V.; Frazer, A.; Morales, A. R.; Kachkovsky, O. D.; Mikhailov, I. A.; Masunov, A. E.; Przhonska, O. V. “Fluorene-based Metal Ion Sensing Probe with High Sensitivity to Zn2+ and Efficient Two-photon Absorption” Journal of Physical Chemistry B 2010, 114, 9313-9321.

  • Yao, S.; Ahn, H.-Y.; Wang, X.; Fu, J.; Van Stryland, E. W.; Hagan, D. J.; *Belfield, K. D. “Donor-Acceptor-Donor Fluorene Derivatives for Two-Photon Fluorescence Lysosomal Imaging” Journal of Organic Chemistry 2010, 75, 3965-3974 (feature article). DOI: 10.1021/jo100554j

  • Andrade, C. D.; Yanez, C. O.; Rodriguez, L.; *Belfield, K. D. “A Series of Fluorene-based Two-photon Absorbing Molecules: Synthesis, Linear and Nonlinear Characterization, and Bioimaging” Journal of Organic Chemistry 2010, 75, 3975-3982. DOI: 10.1021/jo1005075

  • Nguyen, D. M.; Frazer, A., Rodriguez, L.; *Belfield, K. D. “Selective fluorescence sensing of zinc and mercury ions with hydrophilic 1,2,3-triazolyl fluorene probes” Chemistry of Materials 2010, 22, 3472-3481. DOI: 10.1021/cm100599g

  • Morales, A. R.; Luchita, G.; Yanez, C. O.; Bondar, M. V.; Przhonska, O. V.; *Belfield, K. D. “Linear and Nonlinear Photophysics and Bioimaging of an Integrin-targeting Water-soluble Fluorenyl Probe” Organic and Biomolecular Chemistry 2010, 8, 2600-2608. DOI: 10.1039/paperno.

  • Qaddoura, M. A.; *Belfield, K. D. “Probing the Texture of the Calamitic Liquid Crystalline Dimer of 4-(4-Pentenyloxy)benzoic Acid” Materials 2010, 3, 827-840.

  • Kumi, G.; Yanez, C. O.; Belfield, K. D.; *Fourkas, J. T. “High-speed multiphoton absorption polymerization: Fabrication of microfluidic channels with arbitrary cross-sections and high aspect ratios” Lab on a Chip 2010, 10, 1057-1060. DOI:10.1039/B923377F.

  • Passier, R.; Ritchie, J.; Toro, C.; Diaz, C.; Masunov, A. E.; Belfield, K. D.; *Hernandez, F. E. “Thermally Controlled Preferential Molecular Aggregation State in a Thiacarbocyanine Dye” Journal of Chemical Physics 2010, 133, 134508-1-134508-7.

* indicates/precedes the corresponding author