Companion Funding Opportunity: PAR-22-097 , R01 Research Project
Research topics for this FOA are related to brain and other nervous system or neuromuscular function and/or impairment across the lifespan and across generations, and must be relevant to the collaborating LMICs. Applicants are especially encouraged to propose research on co-morbidities and conditions that affect nervous system function across the lifespan. Relevant research for these applications may range from basic science to epidemiological, clinical, health services, translational (e.g. translation of basic research to therapy and of clinical research to applications in the field) and implementation research. Applicants may propose a research and capacity building program on some aspect of neuro-health, brain, other nervous system or neuromuscular function and/or impairment at any stage of life.
Examples of brain, other nervous system and neuromuscular disorders contributing to the burden of disease in LMICs and relevant to this FOA include, but are not limited to, neurodevelopmental disorders (including autism, cerebral palsy, fetal alcohol syndrome, learning disabilities, hydrocephaly, microcephaly), neuromuscular disorders (including muscular dystrophies and inherited or acquired peripheral neuropathies), neurodegenerative diseases (such as Alzheimer's and Parkinson's Diseases), addictive disorders, seizure disorders (such as epilepsy), neuropsychiatric disorders (such as unipolar depression, bipolar disorder, schizophrenia), post-traumatic stress disorder, dementias, encephalopathy, peripheral neuropathies, sensory and motor neuron diseases.
Examples of influences on nervous system function across the lifespan include, but are not limited to: genetic predispositions and epigenetic changes in response to pre-, peri- and post-natal trauma and environmental factors (such as maternal depression, in-utero drug and alcohol exposure, neurotoxic insults, perinatal hypoxia, child abuse and neglect, inadequate environmental stimulation, and nutritional deficiencies), physical and psychological trauma (exposure to violence, sexual and physical abuse, traumatic nervous system injury due to violence and accidents), infection of the nervous system by bacterial, viral and parasitic diseases (such as Zika, HIV/AIDS, malaria, neurocysticercosis, neonatal sepsis) and stroke. Other factors affecting healthy brain development include access to appropriate health care, environmental and socioeconomic factors.
Awards:
Application budgets are limited to $125,000 per year in direct costs, but must reflect the actual needs of the proposed project
Letter of Intent:
30 days prior to the application due date
Full Proposal Submission Deadline:
November 15, 2022
Contacts:
Kathleen Michels, Ph.D.; Fogarty International Center (FIC); Telephone: 301-435-6031
Email: michelsk@nih.gov
