The BioDynamics Laboratory focuses on computational biomechanics and bioengineering, robotics and human-robot interaction, injury prevention and personalized medicine. The lab aims to develop advanced computational methods and software to simulate and understand the dynamics and neuromuscular control of human locomotion; to analyze biomechanical loadings in different biosystems (such as musculoskeletal, vascular, and respiratory systems) under normal, extreme or injurious conditions.
Bioscience and Bioengineering
This research cluster includes both basic and applied research in the areas of neuroscience, neural engineering, regenerative medicine and point-of-care technologies. Research at NJIT includes understanding functions of the brain and spinal cord under normal, injured and diseased states at molecular, cellular and functional levels through experimental, theoretical and computational methods. Regenerative medicine research deals with the process of replacing dysfunctional cells with regenerating cells, tissues or organs to restore normal functions.
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The Cardiovascular Tissue Engineering and Stem Cell Laboratory focuses on understanding and developing therapeutic strategies to repair cardiovascular diseases. The lab develops various in vitro cardiovascular tissue models that involve integrated use of stem cells, biomaterials and biomimetic bioreactors.
The mission of the BioSensor Materials for Advanced Research & Technology (BioSMART) Center is to understand how biological systems communicate with their surroundings by gathering data with sensors on their internal states and environments, measuring the information, and then using that knowledge to develop innovative sensing technologies that employ sustainable materials and greener environmental processes.
The long-term goal of the Center for Brain Imaging is to better understand human brain functioning using integrative neuroimaging and statistical and computational modeling methods. We believe it is essential to understand the complexity of brain function and its development in order to develop effective treatments.
The Center for Injury Biomechanics, Materials and Medicine (CIBM3) is a multi- and interdisciplinary research center focused on understanding, diagnosing and treating brain injuries and concussions using experimental and computational methods. The CIBM3 is involved in both traumatic brain injury (TBI), a major concern among U.S. soldiers and veterans, and mild TBI and concussion in sports injuries, which also raise serious health concerns.
The Circadian Clock Laboratory researches the detailed biomolecular mechanisms of the circadian clock, the bodily and behavioral changes tied to the 24-hour daily cycle that synchronize to daylight and darkness. Increasingly, these patterns are disrupted by modern urban culture, including the omnipresence of artificial light and frequent travel across time zones. To explore the biochemical mechanisms that underlie these daily rhythms, we study the reconstituted in vitro circadian clock from a cyanobacteria, Synecochoccus elongates.
The Computational Neuroanatomy and Neuroinformatics Laboratory aims to fill the gaps in the fields of neurobiology and neuroimaging, especially the need for systematically constructed models of quantitative neurobiological criteria that can aid in clinical diagnoses of cognitive deficits associated with severe brain disorders.
The Computational Orthopaedics and Rehabilitation Engineering (CORE) Laboratory works on decoding the complexities of human movement through experiments and computational methods. In our experiments, we study three-dimensional kinematics, kinetics and electromyography from musclesduring movement. Experimental methods alone cannot decode all of the musculoskeletal system’s complexities, however, so we also develop and validate computational models of human movement during daily activities.
Interdisciplinary research at the Ecohydrology Lab encompasses ecology, hydrology, geographic information science, remote sensing and computer science. We seek mechanistic understandings underlying the geospatial patterns of vegetation dynamics and how they might influence the future of ecosystems and water resources in the context of new and emerging environmental conditions. More specifically, the lab seeks to answer the following questions: What are the mechanisms underlying ecosystem response to anticipated warming and drought?