The Computational Orthopaedics and Rehabilitation Engineering (CORE) Laboratory works on decoding the complexities of human movement through experiments and computational methods. In our experiments, we study three-dimensional kinematics, kinetics and electromyography from musclesduring movement. Experimental methods alone cannot decode all of the musculoskeletal system’s complexities, however, so we also develop and validate computational models of human movement during daily activities. Our insights are used to understand the onset, progression and treatment of musculoskeletal disorders. Current projects include: understanding joint loads during rehabilitation for bone health after spinal cord injury; changes in neuromuscular control strategies with aging; movement patterns in children with cerebral palsy; and building assistive devices for children with cerebral palsy.