Membrane-Mimic Microfluidic Platforms for Sensing and Characterization
Our Approach
We design microfluidic platforms that replicate the structure and function of biological and synthetic membranes enabling precise, real-time analysis of transport dynamics, surface interactions, and fouling behavior under controlled flow conditions. These Membrane Mimic Microfluidic (MMM) systems integrate functional membranes into microchannels, where they serve both as separation media and active electrochemical sensing interfaces.
By coupling these platforms with electrochemical impedance spectroscopy (EIS), we non-invasively monitor changes in membrane-electrolyte interactions and fouling progression.
Key Capabilities
Integrated Membrane Interfaces: Functional membranes embedded within microfluidic devices simulate filtration and surface-binding processes.
Real-Time Impedance Monitoring: EIS captures changes in charge transfer resistance (Rct) associated with analyte accumulation, transport, or fouling events.
Controlled Surrogate Models: Mmimic biological foulants (e.g., bacteria, proteins) to study accumulation dynamics without biohazard risk.
Applications & Impact
Membrane mimic systems bridge fundamental membrane science and applied sensing by enabling direct visualization and quantification of key membrane phenomena, such as:
Biofouling initiation and progression
Membrane-electrolyte interaction characterization
Selective analyte transport across functional barriers
Real-time sensing of surface clogging or performance degradation
These platforms have a far-reaching impact across fields such as environmental engineering, biomedical diagnostics, water treatment, and pharmaceutical membrane processes, offering a miniaturized, data-rich alternative to traditional benchtop systems.