The Mechanobiology Lab focuses on developing integrated computational and experimental tools to understand and harness the role of mechanics in physiological processes such as wound healing and stem cell migration, as well as in pathological processes such as fibrosis, surgical adhesions, scar formation, dry eye disease and cancer progression. Changes in the physical properties of the extracellular environment, due to aging, obesity and diseases such as fibrosis and diabetes, affect many important cellular functions such as migration, proliferation, differentiation and gene expression. Understanding the mechanisms through which cells sense and respond to these physical changes can lead to novel therapeutic modalities and pathways against diseases.

Type
Lab