Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)

Research
Funding Agency:
Funding Agency
ARPA-H
Awards:
Awards

Multiple 
Anticipated Funding Amount:
Letter of Intent:
Letter of Intent
Please contact the program director
Limit on Number of Proposals per Organization:
Preliminary Proposal Deadline:
Preliminary Proposal Due Date(s)
  • Informational Webinar - October 15, 2026 (Register by Oct 12, 2026)
    This is the first of two optional events for the proposer community to learn more about this opportunity, ask questions, and make connections. Registration required, see Special Notice ARPA-H-SN-26-164 for event details.
  • Proposers' Day Event - November 6, 2026 (Register by Oct 28, 2026)
    This is the second of two optional events for the proposer community to learn more about this opportunity, ask questions, and make connections. Registration required, see Special Notice ARPA-H-SN-26-164 for event details.
  • Solution Summary Due - November 30, 2026
    Submitting a summary is required to move forward with this opportunity. After submitting a summary, await feedback from ARPA-H before proceeding.
Full Proposal Submission Deadline:
Full Proposal Submission Deadline

January 22, 2027 
Contacts:
Contacts

Email: surpass@arpa-h.gov  
Description

To achieve the goals of this program ARPA-H is seeking ground-breaking ideas from cross-disciplinary teams in statistics, AI, and clinical trial design, operations, and regulation. Teams will pursue three coordinated technical areas to build faster trials with fewer patients, develop a continuous inference engine for faster decisions, and create an agentic operations layer to reduce time and cost. See solicitation for complete details.

Key Dates:

  • Informational Webinar - October 15, 2026 (Register by Oct 12, 2026)
    This is the first of two optional events for the proposer community to learn more about this opportunity, ask questions, and make connections. Registration required, see Special Notice ARPA-H-SN-26-164 for event details.
  • Proposers' Day Event - November 6, 2026 (Register by Oct 28, 2026)
    This is the second of two optional events for the proposer community to learn more about this opportunity, ask questions, and make connections. Registration required, see Special Notice ARPA-H-SN-26-164 for event details.
  • Solution Summary Due - November 30, 2026
    Submitting a summary is required to move forward with this opportunity. After submitting a summary, await feedback from ARPA-H before proceeding.
  • Proposal Due - January 22, 2027 
    Reference solicitation for full details.

Interested in this opportunity? Download the official solicitation documents which are posted on SAM.gov. The documents outline complete opportunity details including requirements, evaluation criteria, eligibility information, and provide application templates with detailed instructions on how to apply. When ready, you will submit applications to the ARPA-H Solutions site. Sign-in required.