Technology Overview: This NJIT technology is an injectable peptide‑based hydrogel that self‑assembles in situ to form an antibacterial matrix. The hydrogel is composed of engineered peptides that exhibit intrinsic antimicrobial activity while maintaining biocompatibility. Upon injection, the material forms a localized scaffold capable of preventing bacterial colonization and supporting tissue healing. This approach offers a potential alternative to systemic antibiotics, reducing the risk of resistance and systemic side effects.
Industry Pain Point: Post‑surgical and wound infections remain challenging due to antibiotic resistance and limited localized treatment options.
NJIT Solution: This hydrogel provides localized, sustained antibacterial activity via self‑assembling peptide structures.
Key Features & Advantages
- Injectable and self‑assembling
- Intrinsic antibacterial properties
- Localized action with reduced systemic exposure
- Biocompatible and biodegradable
Development Stage: TRL 4–5 – Preclinical laboratory validation completed.
Target Markets
- Surgical and wound care products
- Infection prevention technologies
- Regenerative Medicine Applications
Market Opportunity
- Global wound care market (2026): ~$25B
- CAGR: ~6–7%
- Projected market size (2035): ~$40–45B
Commercial & IP Details
- Patent Status: Issued (US10632172B2)
- Patent Link: https://patents.google.com/patent/US10632172B2
Inventors: Shivani Jaisinghani, Vivek Kumar, Peter Nguyen, Biplab Sarkar
Technology Overview: This NJIT technology introduces a piezoelectric collagen scaffold that converts mechanical loading into localized electrical stimulation, mimicking natural bioelectrical cues found in healing tissues. The scaffold is biocompatible and supports cell attachment while generating electrical signals in response to movement or stress. This bioelectrical stimulation promotes cellular activity and tissue regeneration without external power sources.
Industry Pain Point: Existing scaffolds lack active stimulation to accelerate and guide tissue regeneration.
NJIT Solution: This scaffold provides self‑generated electrical stimulation, enhancing regenerative outcomes.
Key Features & Advantages
- Intrinsic piezoelectric stimulation
- Biocompatible collagen‑based scaffold
- No external power required
- Promotes accelerated tissue regeneration
Development Stage: TRL 4–5 – Laboratory validation demonstrated.
Target Markets
- Regenerative medicine
- Orthopedic and musculoskeletal repair
- Implantable biomedical devices
Market Opportunity
- Global regenerative medicine market (2026): ~$45B
- CAGR: ~15–18%
- Projected market size (2035): >$110B
Commercial & IP Details
- Patent Status: Issued (US11617816B2)
- Patent Link: https://patents.google.com/patent/US11617816B2
Inventors: Treena Arinzeh, Michael Jaffe, Amir Hossein Rajabi
Technology Overview: This is a bioengineered scaffold designed to support tissue regeneration and functional repair by mimicking the structural and mechanical characteristics of native extracellular matrices. The scaffold provides a three‑dimensional framework that promotes cell attachment, proliferation, and differentiation while maintaining mechanical integrity during healing. Its architecture and material composition can be tuned for specific tissue applications, enabling use across both soft and load‑bearing tissues. The platform is compatible with cells, growth factors, and biologics, making it adaptable to a wide range of regenerative strategies.
Industry Pain Point: Conventional tissue scaffolds often lack sufficient mechanical strength or bioactivity, leading to poor integration, delayed healing, or implant failure.
NJIT Solution: This scaffold delivers a mechanically robust, biomimetic structure that enhances cellular response and tissue integration, improving regenerative outcomes.
Key Features & Advantages
- Biomimetic, tunable scaffold architecture
- Enhanced cell attachment and tissue integration
- Improved mechanical stability versus standard polymer scaffolds
- Applicable across multiple tissue types
Development Stage: TRL 4–5 – Laboratory and preclinical validation completed.
Target Markets
- Regenerative medicine
- Orthopedic and soft‑tissue repair
- Biomedical implants
Market Opportunity
- Global regenerative medicine market (2026): ~$45B
- CAGR: ~15–18%
- Projected market size (2035): >$110B
Commercial & IP Details
- Patent Status: Issued (US10420856B2)
- Patent Link: https://patents.google.com/patent/US10420856B2
Inventors: Treena Arinzeh, George Collins, Yee‑Shuan Lee
COMPUTING, COMMUNICATIONS & PHOTONICS
- 06‑052 → MEMS Fiber Optic Microphone
- 14‑017 → Radio Over Fiber Antenna Extender Systems for High Speed Trains
- 23‑007 → High‑Speed Wireless Communications Using Reflected Laser Light
- 23‑003 → Resistive Switching in a RRAM Device
- 23‑013 → Non‑Volatile Processing‑In‑Sensor Accelerator for Imaging Systems
- 23‑019 → Neural Network Acceleration of Image Processing
- 23‑006 → Algorithmic Circuit Design Automation
- 24‑019 → Transformer‑Based Surrogate Model Module for Electric Circuit Performance Modeling
- 21‑021 → Decoding of Graph‑Based Channel Codes via Reinforcement Learning
- 20‑017 → Establishing Consensus in Distributed Communications
- 21‑011 → Identification via Channels and Computer Program Product
- 23‑011 → Indoor Place Prediction
- 20‑030 → Systems and Methods for Privacy‑Preserving Data Hiding
- 20‑031 → Systems and Methods of Detecting Pipe Defects (THz/NDE sensing)
- 22‑021 → Fabrication of Large 3D Single Colloidal Crystals for Bragg Diffraction of Infrared Light
- 21‑022 → Binary Colloidal Quantum Dot Technology
- 15-003→ Embedded Structural Health Monitoring System for Real‑Time Infrastructure Diagnostics
- 19-009 → Dynamic Route Optimization Engine for Real‑Time Traffic‑Aware Navigation
- 23-010→ AI‑Driven Network Optimization Using Predictive Location Intelligence
- 15‑038→ Communication‑Efficient Secret Sharing
- 15‑015→Asymmetric Error Correction & Flash‑Memory Rewriting Using Polar Codes
- 16‑021→Virtual Machine Placement in a Heterogeneous Data Center
- 15‑006→Method and Device for Wireless Topology Discovery for Train Backbone Networks
- 15‑040→Asynchronous Wireless Sensing
- 16‑006→Virtual Machine Resource Utilization in a Data Center
- 08‑006→Apparatus And Method For Space Frequency Block Coding in a Multiple Input Multiple Output Single Carrier Wireless Communication System
- 06‑035→Apparatus and Method for Collaborate Hybrid Automatic Repeat Request (HARQ) in Broadband Wireless Communication System Using Relay Station
- 05‑052→Method and apparatus for ordering retransmissions in an NxM MIMO system
ADVANCED MATERIALS, MANUFACTURING & PROCESS TECHNOLOGIES
- 14‑005 → Continuous Polymer Coating of Particles
- 14‑036 → Porous Hollow Fiber Anti‑Solvent Crystallization‑Based Continuous Polymer Coating on Submicron/Nanoparticles
- 13‑047 → Thin Films with Self‑Assembled Monolayers Embedded on Surfaces
- 14‑011 → Molecular‑Like Hierarchical Self‑Assembly of Monolayers of Mixtures of Particles
- 19‑005 → Spherical Composite Powder
- 14‑008 → Concealed Fastener Window or Curtain Wall Assemblies
- 22‑016 → Protective Material and Associated Protective Wear
- 09‑040→ New Polyesters Ethers Derived from Asymmetrical Monomers (Bisanhydrohexitols) (includes 10377765 & 10364251)
- 13‑052→ System and Method for Fabrication of Uniform Polymer Films Containing Nano and Micro Particles Via Continuous Drying Process
- 12‑032→Foamed Celluloid Process Using Expandable Beads
- 12‑032→ Foamed Celluloid Mortar Propellant Increment Containers
- 06‑057→Fluidized Mixing & Blending of Nanopowders with Secondary Gas Flow
- 06‑057→Fluidized Bed Systems & Methods Including Micro‑Jet Flow
- 06‑057→ Fluidized Bed Systems & Methods Including Micro‑Jet Flow
- 07‑029→ Microfluidic Device for the Assembly & Transport of Microparticles
ENERGY, BATTERIES & DECARBONIZATION
- 18‑032 → High Oxidation State Periodate Battery
- 20‑008 → High‑Capacity Flexible, Printable & Conformal Periodate/Iodate Batteries
- 13‑040 → Thin Film Photovoltaic Modules and Back Contact for Thin Solar Cells
- 13‑038 → CO₂ Removal from Flue Gas by Temperature Swing Absorption
- 18‑034 → Energy Packet Switches
- 12‑042 → Packeted Energy Delivery System and Methods
- 06‑039 → Integrated Biofuel Cell with Aligned Nanotube Electrodes and Method of Use
- 17‑001 → Fabrication of Flexible Conductive Items and Batteries Using Modified Inks (energy‑relevant printed electronics; also fits advanced manufacturing)